EMD-48325

Single-particle
2.83 Å
EMD-48325
3D View Gallery
Deposition: 17/12/2024
Map released: 15/04/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48325

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mkf summary report (pdf.gz) Map-9mkf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Rat TRPV2 bound to AV2-1 agonist

EMD-48325

Single-particle
2.83 Å
EMD-48325
3D View Gallery
Deposition: 17/12/2024
Map released: 15/04/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: transient receptor potential vanilloid 2 bound to AV2-1 agonist
Fitted models: 9mkf

Deposition Authors: Rocereta JA, Pumroy RA, Moiseenkova-Bell VY
Defining AV2-1 as a novel pharmacological probe to target human and rodent TRPV2.
Leipe A, Rocereta JA, Pumroy RA, Leffler A, Schaefer M, Moiseenkova-Bell V, Hill K
(2026) Br.J.Pharmacol. , 183 , 3538 - 3557
PUBMED: 41913383
DOI: doi:10.1111/bph.70413
ISSN: 0007-1188
ASTM: BJPCBH