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EMD-48323
Structure of the IFIT2-IFIT3 heterodimer from Mus musculus
EMD-48323
Single-particle3.22 Å
Deposition: 16/12/2024Map released: 12/03/2025
Last modified: 12/03/2025
Sample Organism:
Mus musculus
Sample: Dimeric complex of Interferon-induced protein with tetratricopeptide repeats 2 and Interferon-induced protein with tetratricopeptide repeats 3
Fitted models: 9mk9
Deposition Authors: Glasner DR
,
Todd C,
Cook BD ,
DUrso A,
Khosla S ,
Estrada E,
Wagner J,
Bartels MD,
Ford P ,
Prych J,
Hatch K ,
Yee BA ,
Ego KM,
Liang Q ,
Holland SR,
Case JB ,
Corbett KD ,
Diamond MS ,
Yeo GW ,
Herzik Jr MA ,
Van Nostrand EL ,
Daugherty MD
Sample: Dimeric complex of Interferon-induced protein with tetratricopeptide repeats 2 and Interferon-induced protein with tetratricopeptide repeats 3
Fitted models: 9mk9
Deposition Authors: Glasner DR
,
Todd C,
Cook BD ,
DUrso A,
Khosla S ,
Estrada E,
Wagner J,
Bartels MD,
Ford P ,
Prych J,
Hatch K ,
Yee BA ,
Ego KM,
Liang Q ,
Holland SR,
Case JB ,
Corbett KD ,
Diamond MS ,
Yeo GW ,
Herzik Jr MA ,
Van Nostrand EL ,
Daugherty MD
Short 5' UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex.
Glasner DR ,
Todd C,
Cook B,
D'Urso A,
Khosla S ,
Estrada E,
Wagner JD ,
Bartels MD,
Ford P ,
Prych J,
Hatch K ,
Yee BA ,
Ego KM,
Liang Q ,
Holland SR,
Case JB ,
Corbett KD ,
Diamond MS ,
Yeo GW ,
Herzik Jr MA ,
Van Nostrand EL ,
Daugherty MD
(2025) bioRxiv
,
Todd C,
Cook B,
D'Urso A,
Khosla S ,
Estrada E,
Wagner JD ,
Bartels MD,
Ford P ,
Prych J,
Hatch K ,
Yee BA ,
Ego KM,
Liang Q ,
Holland SR,
Case JB ,
Corbett KD ,
Diamond MS ,
Yeo GW ,
Herzik Jr MA ,
Van Nostrand EL ,
Daugherty MD
(2025) bioRxiv
Grant Support:
- National Institutes of Health/National Human Genome Research Institute (NIH/NHGRI): U24 HG009889 (United States)
- National Institutes of Health/National Institute of Mental Health (NIH/NIMH): RF1 MH126719 (United States)
- National Institutes of Health/National Human Genome Research Institute (NIH/NHGRI): R01 HG011864 (United States)
- National Institutes of Health/National Human Genome Research Institute (NIH/NHGRI): National Human Genome Research Institute (United States)
- National Institutes of Health/National Human Genome Research Institute (NIH/NHGRI): U24 HG011735 (United States)