EMD-48320

Single-particle
3.24 Å
EMD-48320
3D View Gallery
Deposition: 16/12/2024
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48320

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mk6 summary report (pdf.gz) Map-9mk6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human NBCn2 bound to Compound 38J

EMD-48320

Single-particle
3.24 Å
EMD-48320
3D View Gallery
Deposition: 16/12/2024
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dimeric NBCn2
Fitted models: 9mk6

Deposition Authors: Yang S, Capper MJ, Zilberg G, Warren AL, Wacker D
Structural insights enable drug discovery for the neuronal NBCn2 carbonate transporter
Yang S, Zhao Y, Vatansever S, Zilberg G, Capper MJ, Zhang J, Stamos J, Hutchinson K, Warren AL, Stone AC, Abbassi A, Purisic E, Ho L, Li A, Dai J, Schlessinger A, Zhang B, Wacker D
(2026) Nat Commun
DOI: doi:10.1038/s41467-026-75444-4
ISSN: 2041-1723