EMD-48301

Single-particle
3.3 Å
EMD-48301
3D View Gallery
Deposition: 13/12/2024
Map released: 03/09/2025
Last modified: 10/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48301

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mir summary report (pdf.gz) Map-9mir FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of ALK3-ActRIIB bound to BMP6

EMD-48301

Single-particle
3.3 Å
EMD-48301
3D View Gallery
Deposition: 13/12/2024
Map released: 03/09/2025
Last modified: 10/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Cricetulus griseus
Sample: Ternary complex of ALK3-ActRIIB with BMP6
Fitted models: 9mir

Deposition Authors: Goebel EJ , Saotome K, Franklin MC
CryoEM structure of ALK2:BMP6 reveals distinct mechanism that allow ALK2 to interact with both BMP and activin ligands.
Goebel EJ , Aykul S, Hom WW, Saotome K, Economides AN , Franklin MC, Idone VJ
(2025) PNAS , 122 , e2502788122 - e2502788122
PUBMED: 40854140
DOI: doi:10.1073/pnas.2502788122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: