EMD-48281

Single-particle
3.02 Å
EMD-48281
3D View Gallery
Deposition: 12/12/2024
Map released: 23/04/2025
Last modified: 23/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48281

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mhu summary report (pdf.gz) Map-9mhu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of S. aureus TarGH in complex with Targocil-II and ATP-gamma-S in a catalytically competent conformation

EMD-48281

Single-particle
3.02 Å
EMD-48281
3D View Gallery
Deposition: 12/12/2024
Map released: 23/04/2025
Last modified: 23/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Staphylococcus aureus
Sample: TarGH
Fitted models: 9mhu

Deposition Authors: Peters SC , Worrall LJ, Strynadka NCJ
Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Li FKK , Peters SC , Worrall LJ, Sun T, Hu J, Vuckovic M, Farha M, Palacios A, Caveney NA , Brown ED , Strynadka NCJ
(2025) Nat Commun , 16 , 3224 - 3224
PUBMED: 40185711
DOI: doi:10.1038/s41467-025-58202-w
ISSN: 2041-1723