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EMD-48260

Single-particle
3.3 Å
EMD-48260
3D View Gallery
Deposition: 11/12/2024
Map released: 12/02/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48260
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

PI3KC3-C1 bound to RAB1A. Local refinement of VPS34KD in the inactive state, particle subset

EMD-48260

Single-particle
3.3 Å
EMD-48260
3D View Gallery
Deposition: 11/12/2024
Map released: 12/02/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Phosphatidylinositol-3 kinase class III complex I bound to RAB1A

Deposition Authors: Cook ASI , Chen M , Hurley JH
Structural pathway for PI3-kinase regulation by VPS15 in autophagy.
Cook ASI , Chen M , Nguyen TN , Cabezudo AC , Khuu G , Rao S , Garcia SN , Yang M , Iavarone AT, Ren X , Lazarou M , Hummer G , Hurley JH
(2025) Science , 388 , eadl3787 - eadl3787
PUBMED: 39913640
DOI: doi:10.1126/science.adl3787
ISSN: 1095-9203
ASTM: SCIEAS
Grant Support: