EMD-48258

Single-particle
3.1 Å
EMD-48258
3D View Gallery
Deposition: 11/12/2024
Map released: 12/02/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48258

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

PI3KC3C1 bound to RAB1A, Inactive state, VPS34 kinase domain local refinement

EMD-48258

Single-particle
3.1 Å
EMD-48258
3D View Gallery
Deposition: 11/12/2024
Map released: 12/02/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Phosphatidylinositol-3 kinase class III complex I bound to RAB1A

Deposition Authors: Cook ASI , Chen M , Hurley JH
Structural pathway for PI3-kinase regulation by VPS15 in autophagy.
Cook ASI , Chen M , Nguyen TN , Cabezudo AC , Khuu G , Rao S , Garcia SN , Yang M , Iavarone AT, Ren X , Lazarou M , Hummer G , Hurley JH
(2025) Science , 388 , eadl3787 - eadl3787
PUBMED: 39913640
DOI: doi:10.1126/science.adl3787
ISSN: 1095-9203
ASTM: SCIEAS
Grant Support: