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EMD-48223
De novo designed minibinder complexed with Clostridioides difficile Toxin B
EMD-48223
Single-particle3.02 Å
Deposition: 09/12/2024Map released: 17/09/2025
Last modified: 08/10/2025
Sample Organism:
Clostridioides difficile,
synthetic construct
Sample: De novo designed minibinder complexed with Clostridioides difficile Toxin B
Fitted models: 9mf4
Deposition Authors: Miletic S, Li Z, Ragotte RJ
,
Melnyk R
Sample: De novo designed minibinder complexed with Clostridioides difficile Toxin B
Fitted models: 9mf4
Deposition Authors: Miletic S, Li Z, Ragotte RJ
,
Melnyk R
De novo design of potent inhibitors of clostridial family toxins.
Ragotte RJ ,
Liang H ,
Tam J,
Miletic S,
Berman JM ,
Palou R ,
Weidle C,
Li Z,
Glogl M ,
Beilhartz GL ,
Carr KD ,
Borst AJ ,
Coventry B,
Wang X,
Rubinstein JL ,
Tyers M,
Schramek D,
Melnyk RA ,
Baker D
(2025) PNAS , 122 , e2509329122 - e2509329122
,
Liang H ,
Tam J,
Miletic S,
Berman JM ,
Palou R ,
Weidle C,
Li Z,
Glogl M ,
Beilhartz GL ,
Carr KD ,
Borst AJ ,
Coventry B,
Wang X,
Rubinstein JL ,
Tyers M,
Schramek D,
Melnyk RA ,
Baker D
(2025) PNAS , 122 , e2509329122 - e2509329122
Grant Support: