EMD-48223

Single-particle
3.02 Å
EMD-48223
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Deposition: 09/12/2024
Map released: 17/09/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48223
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9mf4 summary report (pdf.gz) Map and 9mf4 FULL report (pdf.gz)
EMICSS annotations (xml)

De novo designed minibinder complexed with Clostridioides difficile Toxin B

EMD-48223

Single-particle
3.02 Å
EMD-48223
3D View Gallery
Deposition: 09/12/2024
Map released: 17/09/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Clostridioides difficile, synthetic construct
Sample: De novo designed minibinder complexed with Clostridioides difficile Toxin B
Fitted models: 9mf4

Deposition Authors: Miletic S, Li Z, Ragotte RJ , Melnyk R
De novo design of potent inhibitors of clostridial family toxins.
Ragotte RJ , Liang H , Tam J, Miletic S, Berman JM , Palou R , Weidle C, Li Z, Glogl M , Beilhartz GL , Carr KD , Borst AJ , Coventry B, Wang X, Rubinstein JL , Tyers M, Schramek D, Melnyk RA , Baker D
(2025) PNAS , 122 , e2509329122 - e2509329122
PUBMED: 40982695
DOI: doi:10.1073/pnas.2509329122
ISSN: 1091-6490
ASTM: PNASA6