EMD-48220

Single-particle
3.46 Å
EMD-48220
3D View Gallery
Deposition: 08/12/2024
Map released: 10/09/2025
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48220

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9meu summary report (pdf.gz) Map-9meu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CXCR4 tetramer bound to 4 CXCL12 dimers

EMD-48220

Single-particle
3.46 Å
EMD-48220
3D View Gallery
Deposition: 08/12/2024
Map released: 10/09/2025
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CXCR4 tetramer with 4 CXCL12 dimers
Fitted models: 9meu

Deposition Authors: Zhang Z, Patel DJ
CXCR4 mediated recognition of HIV envelope spike and inhibition by CXCL12.
Zhang Z, Zhang H, Zheng L, Chen S, Du S , Xiao J , Patel DJ
(2025) Nat Commun , 16 , 8653 - 8653
PUBMED: 41027939
DOI: doi:10.1038/s41467-025-63815-2
ISSN: 2041-1723