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EMD-48102
NCS.1.1 Fab in complex with the sNAp of A/California/04/2009 (CA09, H1N1) -- 4 Fabs [C4 Reconstruction]
EMD-48102
Single-particle2.29 Å
Deposition: 27/11/2024Map released: 13/08/2025
Last modified: 13/08/2025
Sample Organism:
Homo sapiens,
Influenza A virus
Sample: NCS.1.1 Fab in complex with the sNAp of A/California/04/2009 (CA09, H1N1) -- 4 Fabs
Fitted models: 9ejf
Deposition Authors: Borst AJ
Sample: NCS.1.1 Fab in complex with the sNAp of A/California/04/2009 (CA09, H1N1) -- 4 Fabs
Fitted models: 9ejf
Deposition Authors: Borst AJ
Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies.
Lederhofer J ,
Borst AJ ,
Nguyen L,
Gillespie RA ,
Williams CJ,
Walker EL,
Raab JE,
Yap C,
Ellis D,
Creanga A ,
Tan HX,
Do THT,
Ravichandran M ,
McDermott AB ,
Le Sage V,
Andrews SF ,
Graham BS,
Wheatley AK ,
Reed DS ,
King NP ,
Kanekiyo M
(2025) Nat Commun , 16 , 7068 - 7068
,
Borst AJ ,
Nguyen L,
Gillespie RA ,
Williams CJ,
Walker EL,
Raab JE,
Yap C,
Ellis D,
Creanga A ,
Tan HX,
Do THT,
Ravichandran M ,
McDermott AB ,
Le Sage V,
Andrews SF ,
Graham BS,
Wheatley AK ,
Reed DS ,
King NP ,
Kanekiyo M
(2025) Nat Commun , 16 , 7068 - 7068
Grant Support:
- Bill & Melinda Gates Foundation: (United States)