EMD-48099

Single-particle
3.6 Å
EMD-48099
3D View Gallery
Deposition: 27/11/2024
Map released: 05/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48099

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ejb summary report (pdf.gz) Map-9ejb FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human FANCJ helicase bound to a fork DNA in the open state

EMD-48099

Single-particle
3.6 Å
EMD-48099
3D View Gallery
Deposition: 27/11/2024
Map released: 05/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of Human FANCJ with fork DNA in open state
Fitted models: 9ejb

Deposition Authors: You Q , Li H
Cryo-EM structures of human FANCJ reveal the mechanism of G-quadruplex unwinding and disease-associated mutations.
You Q , Kakusho N , Sasanuma H, Masai H , Li H
(2026) Nat Commun , 17
PUBMED: 42457705
DOI: doi:10.1038/s41467-026-75715-0
ISSN: 2041-1723