EMD-47968

Single-particle
3.36 Å
EMD-47968
3D View Gallery
Deposition: 19/11/2024
Map released: 18/06/2025
Last modified: 10/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47968
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ef2 summary report (pdf.gz) Map and 9ef2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin candidate 2, open conformation

EMD-47968

Single-particle
3.36 Å
EMD-47968
3D View Gallery
Deposition: 19/11/2024
Map released: 18/06/2025
Last modified: 10/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Protein complex of wild type integrin alpha-5 beta-1 with computationally designed protein NeoNectin candidate 2
Fitted models: 9ef2

Deposition Authors: Werther R , Nguyen A , Estrada Alamo KA, Wang X , Campbell MG
De Novo Design of Integrin alpha 5 beta 1 Modulating Proteins to Enhance Biomaterial Properties.
Wang X , Guillem-Marti J , Kumar S , Lee DS , Cabrerizo-Aguado D , Werther R , Alamo KAE , Zhao YT , Nguyen A , Kopyeva I , Huang B , Li J, Hao Y, Li X , Brizuela-Velasco A , Murray A, Gerben S , Roy A , DeForest CA , Springer T, Ruohola-Baker H , Cooper JA , Campbell MG , Manero JM , Ginebra MP , Baker D
(2025) Adv Mater , 37 , e2500872 - e2500872
PUBMED: 40489013
DOI: doi:10.1002/adma.202500872
ISSN: 1521-4095