EMD-47928

Single-particle
3.89 Å
EMD-47928
3D View Gallery
Deposition: 15/11/2024
Map released: 20/08/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47928

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ecz summary report (pdf.gz) Map-9ecz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SARS-CoV-2 spike protein in complex with human neutralizing antibody WRAIR-2008 (focused refinement of NTD and WRAIR-2008)

EMD-47928

Single-particle
3.89 Å
EMD-47928
3D View Gallery
Deposition: 15/11/2024
Map released: 20/08/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: WRAIR-2008 antibody Fab bound to the N-terminal domain of the spike glycoprotein (focused refinement)
Fitted models: 9ecz

Deposition Authors: Jensen JL , Thomas PV, Joyce MG
First-generation N-terminal domain supersite public antibodies retain activity against Omicron-derived lineages and protect mice against Omicron BA.5 challenge.
Dussupt V , Jensen JL , Thomas PV, Mendez-Rivera L, Lal KG, Zemil McCrea M, Swafford I , Hernandez J, Sankhala RS, Rao M, Arora J , Hajduczki A, Jian N, Rees PA, Showell-De Leon I, Smith G, Smith L, Wasson D, Schmid A, Teng IT, Zhou T , Kwong PD , Currier JR, Reiley WW, Paquin-Proulx D , Polonis VR , Collins ND, Michael NL, Joyce MG , Krebs SJ
(2025) Mbio , 16 , e0103625 - e0103625
PUBMED: 40882161
DOI: doi:10.1128/mbio.01036-25
ISSN: 2150-7511