Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-47823

Single-particle
2.0 Å
EMD-47823
3D View Gallery
Deposition: 09/11/2024
Map released: 26/02/2025
Last modified: 02/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47823
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ea0 summary report (pdf.gz) Map and 9ea0 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the prefusion HKU5-19s Spike trimer (conformation 1)

EMD-47823

Single-particle
2.0 Å
EMD-47823
3D View Gallery
Deposition: 09/11/2024
Map released: 26/02/2025
Last modified: 02/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Pipistrellus bat coronavirus HKU5
Sample: Prefusion HKU5-19s S trimer
Fitted models: 9ea0

Deposition Authors: Park YJ , Gen R, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses.
Park YJ , Liu C, Lee J, Brown JT, Ma CB, Liu P, Gen R, Xiong Q, Zepeda SK, Stewart C, Addetia A, Craig CJ, Tortorici MA , Alshukairi AN, Starr TN, Yan H , Veesler D
(2025) Cell , 188 , 1711 - 1728.e21
PUBMED: 39922192
DOI: doi:10.1016/j.cell.2024.12.032
ISSN: 1097-4172