EMD-47752

Single-particle
3.58 Å
EMD-47752
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Deposition: 07/11/2024
Map released: 11/03/2026
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47752
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e93 summary report (pdf.gz) Map and 9e93 FULL report (pdf.gz)
EMICSS annotations (xml)

Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H

EMD-47752

Single-particle
3.58 Å
EMD-47752
3D View Gallery
Deposition: 07/11/2024
Map released: 11/03/2026
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Pan troglodytes, Escherichia coli BL21(DE3), Homo sapiens, Human immunodeficiency virus 1
Sample: Ternary complex of APOBEC3H and Vif of HIV-1
Fitted models: 9e93

Deposition Authors: Matsuo H, Skorupka KA
HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation.
Skorupka KA, Matsuoka K, Hassan B, Ghirlando R, Balachandran V, Chen TH, Walters KJ, Schiffer CA, Wolf M, Iwatani Y, Matsuo H
(2025) Nat Commun , 16 , 5879 - 5879
PUBMED: 40593686
DOI: doi:10.1038/s41467-025-60984-y
ISSN: 2041-1723