EMD-47733

Helical reconstruction
2.8 Å
EMD-47733
3D View Gallery
Deposition: 06/11/2024
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47733

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9e8w summary report (pdf.gz) Map-9e8w FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Complex fibril structure of MSA alpha-synuclein with CNS-11g at 6 hours

EMD-47733

Helical reconstruction
2.8 Å
EMD-47733
3D View Gallery
Deposition: 06/11/2024
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha-synuclein
Fitted models: 9e8w

Deposition Authors: Lu J , Sawaya MR , Ge P , Boyer DR , Eisenberg DS

The small molecule CNS-11g forms amyloid-like fibrils that disassemble pathological alpha-synuclein fibrils
Lu J , Sawaya MR , Cheng XY, Murrali MG , Ge P , Jiang YX , Cascio D , Lutter L , Boyer DR , Williams CK, Shino M, Feigon J, Chaturvedi S, Alexandrova A, Eisenberg DS
To Be Published