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EMD-47700
ACKR3 phosphorylated by GRK5 in complex with arrestin2 and Fab7
EMD-47700
Single-particle3.4 Å
Deposition: 04/11/2024Map released: 02/04/2025
Last modified: 15/10/2025
Sample Organism:
Bos taurus,
Homo sapiens,
synthetic construct
Sample: human ACKR3 phosphorylated by GRK5 in complex with Arrestin3
Fitted models: 9e82
Deposition Authors: Chen Q
,
Fuller J
,
Tesmer JJG
Sample: human ACKR3 phosphorylated by GRK5 in complex with Arrestin3
Fitted models: 9e82
Deposition Authors: Chen Q
,
Fuller J
,
Tesmer JJG
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Chen Q
,
Schafer CT
,
Mukherjee S
,
Wang K
,
Gustavsson M
,
Fuller JR
,
Tepper K,
Lamme TD
,
Aydin Y
,
Agrawal P,
Terashi G
,
Yao XQ,
Kihara D
,
Kossiakoff AA
,
Handel TM
,
Tesmer JJG
(2025) Nature , 643 , 280 - 287
,
Schafer CT
,
Mukherjee S
,
Wang K
,
Gustavsson M
,
Fuller JR
,
Tepper K,
Lamme TD
,
Aydin Y
,
Agrawal P,
Terashi G
,
Yao XQ,
Kihara D
,
Kossiakoff AA
,
Handel TM
,
Tesmer JJG
(2025) Nature , 643 , 280 - 287
Grant Support:
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA254402 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM117372 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI161880 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA221289 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA023168 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM137505 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): HL071818 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA023168 (United States)
- Walther Cancer Foundation: (United States)
- The Robertson Foundation: Irvington Postdoctoral Fellowship (United States)
- Villum Fonden: 00025326 (Denmark)
- Ralph W. and Grace M. Showalter Research Trust: 4480108 (United States)
