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EMD-47571

Single-particle
3.15 Å
EMD-47571
3D View Gallery
Deposition: 30/10/2024
Map released: 20/11/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47571
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e6k summary report (pdf.gz) Map and 9e6k FULL report (pdf.gz)
EMICSS annotations (xml)

Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.

EMD-47571

Single-particle
3.15 Å
EMD-47571
3D View Gallery
Deposition: 30/10/2024
Map released: 20/11/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of ADAM17 disintegrin-cysteine rich domain
Fitted models: 9e6k

Deposition Authors: Saha N, De La Cruz MJ, Goldgur Y, Nikolov DB
Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.
Saha N, Lee SG, Brockmann EC , de la Cruz MJ, Goldgur Y, Mendoza RP, Stanchina E, Love TM , Marvald J, Xu Y, Xu K, Himanen JP, Lamminmaki U, Veach D, Nikolov DB
(2024) Biomed Pharmacother , 180 , 117605 - 117605
PUBMED: 39461016
DOI: doi:10.1016/j.biopha.2024.117605
ISSN: 1950-6007