EMD-47571

Single-particle
3.15 Å
EMD-47571
3D View Gallery
Deposition: 30/10/2024
Map released: 20/11/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47571

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9e6k summary report (pdf.gz) Map-9e6k FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.

EMD-47571

Single-particle
3.15 Å
EMD-47571
3D View Gallery
Deposition: 30/10/2024
Map released: 20/11/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of ADAM17 disintegrin-cysteine rich domain
Fitted models: 9e6k

Deposition Authors: Saha N, De La Cruz MJ, Goldgur Y, Nikolov DB
Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.
Saha N, Lee SG, Brockmann EC , de la Cruz MJ, Goldgur Y, Mendoza RP, Stanchina E, Love TM , Marvald J, Xu Y, Xu K, Himanen JP, Lamminmaki U, Veach D, Nikolov DB
(2024) Biomed Pharmacother , 180 , 117605 - 117605
PUBMED: 39461016
DOI: doi:10.1016/j.biopha.2024.117605
ISSN: 1950-6007