Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-47477

Single-particle
3.06 Å
EMD-47477
3D View Gallery
Deposition: 23/10/2024
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47477
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e3b summary report (pdf.gz) Map and 9e3b FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of PRMT5/WDR77 in complex with 6S complex

EMD-47477

Single-particle
3.06 Å
EMD-47477
3D View Gallery
Deposition: 23/10/2024
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PRMT5/WDR77 in complex with 6S
Fitted models: 9e3b

Deposition Authors: Jin CY, Hunkeler M , Fischer ES
Substrate adaptors are flexible tethering modules that enhance substrate methylation by the arginine methyltransferase PRMT5.
Jin CY, Hunkeler M , Mulvaney KM, Sellers WR, Fischer ES
(2025) J Biol Chem , 301 , 108165 - 108165
PUBMED: 39793893
DOI: doi:10.1016/j.jbc.2025.108165
ISSN: 1083-351X
ASTM: JBCHA3