EMD-47370

Single-particle
3.1 Å
EMD-47370
3D View Gallery
Deposition: 19/10/2024
Map released: 09/07/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47370

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9e0t summary report (pdf.gz) Map-9e0t FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human cytoplasmic dynein-1 bound to LIS1 in the presence of ATP

EMD-47370

Single-particle
3.1 Å
EMD-47370
3D View Gallery
Deposition: 19/10/2024
Map released: 09/07/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human Cytoplasmic dynein-1 bound to LIS1
Fitted models: 9e0t

Deposition Authors: Nguyen KHV , Kendrick AA , Leschziner AE
Cryo-EM captures early intermediate steps in dynein activation by LIS1.
Nguyen KHV , Karasmanis EP , Kendrick AA , Reck-Peterson SL , Leschziner AE
(2025) Nat Commun , 16 , 7054 - 7054
PUBMED: 40750582
DOI: doi:10.1038/s41467-025-62185-z
ISSN: 2041-1723