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EMD-47364

Single-particle
2.0 Å
EMD-47364
3D View Gallery
Deposition: 18/10/2024
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47364
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e0o summary report (pdf.gz) Map and 9e0o FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of inducible Lysine decarboxylase from Hafnia alvei L-hydrazino-Lysine analog at 2.04 Angstrom resolution

EMD-47364

Single-particle
2.0 Å
EMD-47364
3D View Gallery
Deposition: 18/10/2024
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Hafnia alvei ATCC 51873
Sample: Inducible Lysine decarboxylase from Hafnia alvei with bound L-hydrazino-lysine inhibitor
Fitted models: 9e0o

Deposition Authors: Duhoo Y , Desfosses A , Gutsche I , Doukov TI, Berkowitz DB
alpha-Hydrazino Acids Inhibit Pyridoxal Phosphate-Dependent Decarboxylases via "Catalytically Correct" Ketoenamine Tautomers: A Special Motif for Chemical Biology and Drug Discovery?
Baine JM , Duhoo Y , Doukov T , Desfosses A , Bisello G , Beio ML , Bauer O , Perduca M , Bacia-Verloop M , Bertoldi M , Phillips RS , Gutsche I , Berkowitz DB
(2025) ACS Catal , 15 , 8204 - 8218
PUBMED: 40401103
DOI: doi:10.1021/acscatal.5c00326
ISSN: 2155-5435