EMD-47353

Single-particle
3.72 Å
EMD-47353
3D View Gallery
Deposition: 17/10/2024
Map released: 18/02/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47353

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9e09 summary report (pdf.gz) Map-9e09 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure a single nucleosome (2) focus of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

EMD-47353

Single-particle
3.72 Å
EMD-47353
3D View Gallery
Deposition: 17/10/2024
Map released: 18/02/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: DNMT3A/3B tetramer bound to di-nucleosome
Fitted models: 9e09

Deposition Authors: Xie X, Zhou XE, Worden EJ , Jones PA
Nucleosome spacing regulates linker methylation by DNMT3A2/3B3.
Xie X, Liu M, Chua GNL, Zhou XE, Dykstra ML, Liu S, Jones PA, Worden EJ
(2026) Mol Cell , 86 , 834 - 850.e9
PUBMED: 41742418
DOI: doi:10.1016/j.molcel.2026.01.030
ISSN: 1097-2765
ASTM: MOCEFL