EMD-47344

Single-particle
3.75 Å
EMD-47344
3D View Gallery
Deposition: 17/10/2024
Map released: 25/02/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47344

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9e00 summary report (pdf.gz) Map-9e00 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

EMD-47344

Single-particle
3.75 Å
EMD-47344
3D View Gallery
Deposition: 17/10/2024
Map released: 25/02/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: DNMT3A/3B tetramer bound to di-nucleosome
Fitted models: 9e00

Deposition Authors: Xie X, Zhou XE, Worden EJ , Jones PA
Nucleosome spacing regulates linker methylation by DNMT3A2/3B3.
Xie X, Liu M, Chua GNL, Zhou XE, Dykstra ML, Liu S, Jones PA, Worden EJ
(2026) Mol Cell , 86 , 834 - 850.e9
PUBMED: 41742418
DOI: doi:10.1016/j.molcel.2026.01.030
ISSN: 1097-2765
ASTM: MOCEFL