EMD-47336

Single-particle
2.38 Å
EMD-47336
3D View Gallery
Deposition: 17/10/2024
Map released: 12/02/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47336

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin - focused map on xanthine

EMD-47336

Single-particle
2.38 Å
EMD-47336
3D View Gallery
Deposition: 17/10/2024
Map released: 12/02/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of RyR2-R2474S, Calstabin-2, and Calmodulin

Deposition Authors: Miotto MC , Marks AR
Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disorders.
Miotto MC , Luna-Figueroa E, Tchagou C, Bahlouli L, Reiken S , Dridi H, Liu Y , Weninger G , Marks AR
(2025) PNAS , 122 , e2422082122 - e2422082122
PUBMED: 40512792
DOI: doi:10.1073/pnas.2422082122
ISSN: 1091-6490
ASTM: PNASA6