Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-47296

Single-particle
3.1 Å
EMD-47296 Deposition: 11/10/2024
Map released: 11/12/2024
Last modified: 11/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47296

Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with positive allosteric modulator BPAM-344 and channel blocker Nephilatoxin-8

EMD-47296

Single-particle
3.1 Å
EMD-47296 Deposition: 11/10/2024
Map released: 11/12/2024
Last modified: 11/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with positive allosteric modulator BPAM-344 and channel blocker Nephilatoxin-8
Fitted models: 9dxr

Deposition Authors: Gangwar SP , Yen LY, Newton TP , Yelshanskaya MV, Sobolevsky AI
Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels.
Gangwar SP , Yelshanskaya MV, Aktolun M, Yen LY, Newton TP , Stromgaard K , Kurnikova MG , Sobolevsky AI
(2024) Nat Commun , 15 , 10257 - 10257
PUBMED: 39592599
DOI: doi:10.1038/s41467-024-54538-x
ISSN: 2041-1723