EMD-47274

Single-particle
2.9 Å
EMD-47274
3D View Gallery
Deposition: 10/10/2024
Map released: 16/07/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47274

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dwy summary report (pdf.gz) Map-9dwy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human MCT8 in complex with thyroid hormone T3

EMD-47274

Single-particle
2.9 Å
EMD-47274
3D View Gallery
Deposition: 10/10/2024
Map released: 16/07/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human MCT8 in complex with thyroid hormone T3
Fitted models: 9dwy

Deposition Authors: Ge Y, Dou T, Jiang J, Huang P
Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1.
Ge Y, Dou T, Nguyen TU, Yadav GP, Wensel TG, Jiang J, Huang P
(2025) Cell , 188 , 5576 - 5588.e17
PUBMED: 40680733
DOI: doi:10.1016/j.cell.2025.06.032
ISSN: 1097-4172