EMD-47269

Single-particle
3.3 Å
EMD-47269
3D View Gallery
Deposition: 10/10/2024
Map released: 06/08/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47269

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dww summary report (pdf.gz) Map-9dww FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map)

Ternary complex of CRBN-DDB1-PDE6D with FPFT-2216

EMD-47269

Single-particle
3.3 Å
EMD-47269
3D View Gallery
Deposition: 10/10/2024
Map released: 06/08/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of CRBN-DDB1-PDE6D with FPFT-2216
Fitted models: 9dww

Deposition Authors: Baek K , Fischer ES
Unveiling the hidden interactome of CRBN molecular glues.
Baek K , Metivier RJ, Roy Burman SS , Bushman JW, Yoon H, Lumpkin RJ, Ryan JK, Abeja DM, Lakshminarayan M, Yue H , Ojeda S , Xiong Y , Che J, Verano AL , Schmoker AM, Gray NS , Donovan KA , Fischer ES
(2025) Nat Commun , 16 , 6831 - 6831
PUBMED: 40707481
DOI: doi:10.1038/s41467-025-62099-w
ISSN: 2041-1723