EMD-47258

Single-particle
3.2 Å
EMD-47258
3D View Gallery
Deposition: 09/10/2024
Map released: 16/04/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47258

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dwn summary report (pdf.gz) Map-9dwn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

hTHIK1 Cryo-EM structure in GDN detergent

EMD-47258

Single-particle
3.2 Å
EMD-47258
3D View Gallery
Deposition: 09/10/2024
Map released: 16/04/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: THIK1 ion channel dimer
Fitted models: 9dwn

Deposition Authors: Riel EB , Riegelhaupt PM
The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel.
Riel EB , Bu W, Joseph TT, Khajoueinejad L , Eckenhoff RG, Riegelhaupt PM
(2025) PNAS , 122 , e2421654122 - e2421654122
PUBMED: 40178898
DOI: doi:10.1073/pnas.2421654122
ISSN: 1091-6490
ASTM: PNASA6