EMD-47199
Thermus thermophilus MreC-MreD complex with an internal MreD BRIL fusion and an anti-BRIL Fab.
EMD-47199
Single-particle3.6 Å
Deposition: 07/10/2024Map released: 15/10/2025
Last modified: 29/04/2026
Sample Organism:
Thermus thermophilus,
synthetic construct,
Escherichia coli
Sample: Complex containing two copies of TtMreC and TtMreD-BRIL with two BAG2 anti-BRIL Fabs bound.
Fitted models: 9dvb
Deposition Authors: Gilman MSA
,
Kruse AC
Sample: Complex containing two copies of TtMreC and TtMreD-BRIL with two BAG2 anti-BRIL Fabs bound.
Fitted models: 9dvb
Deposition Authors: Gilman MSA
,
Kruse AC
Conformational regulation of two essential activators of bacterial cell elongation.
Gilman MSA ,
Shlosman I,
Guerra DDS,
Domecillo M,
Fivenson EM,
Bourett C,
Bernhardt TG ,
Polizzi NF,
Loparo JJ ,
Kruse AC
(2025) PNAS , 122 , e2514198122 - e2514198122
,
Shlosman I,
Guerra DDS,
Domecillo M,
Fivenson EM,
Bourett C,
Bernhardt TG ,
Polizzi NF,
Loparo JJ ,
Kruse AC
(2025) PNAS , 122 , e2514198122 - e2514198122
Grant Support:
- Howard Hughes Medical Institute (HHMI): Investigator Funds (United States)
- Howard Hughes Medical Institute (HHMI): Hanna H. Gray Fellows program (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): U19 AI158028 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM114065 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01 AI083365 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R00 GM135519 (United States)
- National Science Foundation (NSF, United States): Graduate Research Fellowship Award (United States)
- Other private: Van Maanen Fellowship from the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School (United States)
- Other private: Innovation Research Fund of the Dana-Farber Cancer Institute (United States)