EMD-47134

Single-particle
7.02 Å
EMD-47134
3D View Gallery
Deposition: 26/09/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47134

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dry summary report (pdf.gz) Map-9dry FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CHIP U-box dimer bound to Fab 2F1

EMD-47134

Single-particle
7.02 Å
EMD-47134
3D View Gallery
Deposition: 26/09/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CHIP U-box dimer bound to Fab 2F1
Fitted models: 9dry

Deposition Authors: Unnikrishnan A, Southworth D
Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms.
Chung DH, Connelly EJ, Unnikrishnan A, Chuo SW , Wucherer K , Nadel CM , Gestwicki JE, Southworth DR, Craik CS
(2025) J Biol Chem , 301 , 108220 - 108220
PUBMED: 39863102
DOI: doi:10.1016/j.jbc.2025.108220
ISSN: 1083-351X
ASTM: JBCHA3
Grant Support: