EMD-47114

Single-particle
2.9 Å
EMD-47114
3D View Gallery
Deposition: 24/09/2024
Map released: 11/12/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47114

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dqj summary report (pdf.gz) Map-9dqj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-3945

EMD-47114

Single-particle
2.9 Å
EMD-47114
3D View Gallery
Deposition: 24/09/2024
Map released: 11/12/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: EP-3945-bound MRGPRD-Gq complex
Fitted models: 9dqj

Deposition Authors: Cao C, Wang C, Liu Y, Fay JF, Roth BL
High-affinity agonists reveal recognition motifs for the MRGPRD GPCR.
Wang C, Liu Y, Lanier M, Yeager A, Singh I, Gumpper RH, Krumm BE, DeLeon C, Zhang S, Boehm M, Pittner R, Baron A, Dvorak L, Bacon C, Shoichet BK, Martinborough E, Fay JF, Cao C, Roth BL
(2024) Cell Rep , 43 , 114942 - 114942
PUBMED: 39580805
DOI: doi:10.1016/j.celrep.2024.114942
ISSN: 2211-1247