EMD-47111

Single-particle
3.0 Å
EMD-47111
3D View Gallery
Deposition: 23/09/2024
Map released: 25/12/2024
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47111

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dqd summary report (pdf.gz) Map-9dqd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

cryo-EM structure of human Cereblon/DDB1 in complex with a non-traditional CRBN binder

EMD-47111

Single-particle
3.0 Å
EMD-47111
3D View Gallery
Deposition: 23/09/2024
Map released: 25/12/2024
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CREBN-DDB1 plus a non-traditional CRBN binder
Fitted models: 9dqd

Deposition Authors: Zhu J , Pagarigan B
Development of a Buchwald-Hartwig Amination for an Accelerated Library Synthesis of Cereblon Binders.
Lejava A, Miseo GA , Phan T, Zhu J , Powers HL, Li J, Mortensen DS , Zapf CW , Khambatta G , Buenviaje J, Holmberg-Douglas N
(2025) Acs Med.Chem.Lett. , 16 , 89 - 95
PUBMED: 39811117
DOI: doi:10.1021/acsmedchemlett.4c00462
ISSN: 1948-5875
Grant Support: