EMD-47031

Single-particle
4.0 Å
EMD-47031
3D View Gallery
Deposition: 16/09/2024
Map released: 01/10/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47031

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dn6 summary report (pdf.gz) Map-9dn6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Insulin receptor bound with de novo designed agonist called "RF-405".

EMD-47031

Single-particle
4.0 Å
EMD-47031
3D View Gallery
Deposition: 16/09/2024
Map released: 01/10/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Insulin receptor bound with de novo designed agonist RF-405
Fitted models: 9dn6

Deposition Authors: Bai XC
Tuning insulin receptor signaling using de novo-designed agonists.
Wang X, Cardoso S, Cai K, Venkatesh P, Hung A, Ng M, Hall C, Coventry B, Lee DS, Chowhan R, Gerben S, Li J, An W, Hon M, Gao M, Liao YC, Accili D, Choi E , Bai XC, Baker D
(2025) Mol Cell , 85 , 4064
PUBMED: 41086805
DOI: doi:10.1016/j.molcel.2025.09.020
ISSN: 1097-2765
ASTM: MOCEFL