EMD-47016

Single-particle
1.82 Å
EMD-47016
3D View Gallery
Deposition: 14/09/2024
Map released: 27/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47016

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dmu summary report (pdf.gz) Map-9dmu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of IMPDH2 bound to IMP and GAD

EMD-47016

Single-particle
1.82 Å
EMD-47016
3D View Gallery
Deposition: 14/09/2024
Map released: 27/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of IMPDH2 bound to IMP and GAD
Fitted models: 9dmu

Deposition Authors: Chen YJ , Li B, Parada LF
Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma.
Chen YJ , Iyer SV , Hsieh DC , Li B, Elias HK , Wang T, Li J, Ganbold M, Lien MC, Peng YC, Xie XP , Jayewickreme CD, van den Brink MRM , Brady SF , Lim SK, Parada LF
(2024) Nature , 636 , 466 - 473
PUBMED: 39567689
DOI: doi:10.1038/s41586-024-08224-z
ISSN: 1476-4687
ASTM: NATUAS