EMD-46946

Helical reconstruction
3.3 Å
EMD-46946
3D View Gallery
Deposition: 08/09/2024
Map released: 22/01/2025
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46946

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dk8 summary report (pdf.gz) Map-9dk8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TRIF TIR Filament Cryo-EM Structure

EMD-46946

Helical reconstruction
3.3 Å
EMD-46946
3D View Gallery
Deposition: 08/09/2024
Map released: 22/01/2025
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TRIF TIR Filament Cryo-EM Structure
Fitted models: 9dk8

Deposition Authors: Manik MK , Xiao L, Wu H
Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM.
Manik MK , Pan M , Xiao L, Gu W, Kim H, Pospich S , Hedger A, Vajjhala PR, Lee MYL, Qian X, Landsberg MJ , Ve T, Nanson JD , Raunser S , Stacey KJ, Wu H , Kobe B
(2025) PNAS , 122 , e2418988122 - e2418988122
PUBMED: 39786929
DOI: doi:10.1073/pnas.2418988122
ISSN: 1091-6490
ASTM: PNASA6