EMD-46828

Single-particle
3.35 Å
EMD-46828
3D View Gallery
Deposition: 02/09/2024
Map released: 30/04/2025
Last modified: 07/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46828
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dgi summary report (pdf.gz) Map and 9dgi FULL report (pdf.gz)
EMICSS annotations (xml)

Cannabinoid receptor 1-Gi complex with novel ligand

EMD-46828

Single-particle
3.35 Å
EMD-46828
3D View Gallery
Deposition: 02/09/2024
Map released: 30/04/2025
Last modified: 07/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Signaling complex of the cannabinoid receptor 1 bound to Gi
Fitted models: 9dgi

Deposition Authors: Tummino TA , Iliopoulos-Tsoutsouvas C , Braz JM , O'Brien ES , Krishna Kumar K , Makriyannis M, Basbaum AI , Shoichet BK
Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects.
Tummino TA , Iliopoulos-Tsoutsouvas C , Braz JM , O'Brien ES , Stein RM, Craik V , Tran NK, Ganapathy S, Liu F, Shiimura Y , Tong F , Ho TC, Radchenko DS , Moroz YS, Rosado SR, Bhardwaj K , Benitez J, Liu Y , Kandasamy H, Normand C, Semache M, Sabbagh L , Glenn I, Irwin JJ , Kumar KK, Makriyannis A , Basbaum AI , Shoichet BK
(2025) Nat Commun , 16 , 2237 - 2237
PUBMED: 40044644
DOI: doi:10.1038/s41467-025-57136-7
ISSN: 2041-1723