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EMD-46820

Single-particle
4.1 Å
EMD-46820
3D View Gallery
Deposition: 30/08/2024
Map released: 12/02/2025
Last modified: 09/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46820
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dfx summary report (pdf.gz) Map and 9dfx FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of a SUR1/Kir6.2 ATP-sensitive potassium channel in the presence of Aekatperone in the closed conformation

EMD-46820

Single-particle
4.1 Å
EMD-46820
3D View Gallery
Deposition: 30/08/2024
Map released: 12/02/2025
Last modified: 09/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mesocricetus auratus
Sample: Kir6.2/SUR1 closed channel in complex with Aekatperone
Fitted models: 9dfx

Deposition Authors: Driggers CM , ElSheikh A , Shyng S-L
AI-based discovery and cryoEM structural elucidation of a K ATP channel pharmacochaperone.
Elsheikh A, Driggers CM , Truong HH, Yang Z, Allen J, Henriksen NM, Walczewska-Szewc K , Shyng SL
(2025) eLife , 13
PUBMED: 40135739
DOI: doi:10.7554/eLife.103159
ISSN: 2050-084X