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EMD-46760
Cryo-EM structure of neutralizing human antibody D48 in complex with HSV-1 glycoprotein B trimer gB-Ecto.516P
EMD-46760
Single-particle3.08 Å
Deposition: 27/08/2024Map released: 10/09/2025
Last modified: 12/11/2025
Sample Organism:
Human alphaherpesvirus 1,
Homo sapiens
Sample: D48 in complex with HSV-1 gB ectodomain trimer
Fitted models: 9dd8
Deposition Authors: Roark RS, Shapiro L
,
Kwong PD
Sample: D48 in complex with HSV-1 gB ectodomain trimer
Fitted models: 9dd8
Deposition Authors: Roark RS, Shapiro L
,
Kwong PD
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B.
Roark RS,
Schaub AJ,
Shi W,
Wang M,
Bahna FA,
Becker JE,
Biju A ,
Chong S,
Du H,
Guo Y ,
Hong H ,
Katsamba PS,
Mannepalli SM,
Olia AS,
Ou L ,
Rubin SK,
Sabo Y ,
Suleiman M ,
Wells ML,
Zhang B,
Cheng C ,
Glasgow A ,
Ho DD,
Huang Y ,
Pierson TC,
Rawi R ,
Zhou T ,
Shapiro L ,
Kwong PD
(2025) Nat Microbiol , 10 , 2966 - 2980
,
Chong S,
Du H,
Guo Y ,
Hong H ,
Katsamba PS,
Mannepalli SM,
Olia AS,
Ou L ,
Rubin SK,
Sabo Y ,
Suleiman M ,
Wells ML,
Zhang B,
Cheng C ,
Glasgow A ,
Ho DD,
Huang Y ,
Pierson TC,
Rawi R ,
Zhou T ,
Shapiro L ,
Kwong PD
(2025) Nat Microbiol , 10 , 2966 - 2980
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