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EMD-46721

Single-particle
2.76 Å
EMD-46721
3D View Gallery
Deposition: 23/08/2024
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46721
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dbn summary report (pdf.gz) Map and 9dbn FULL report (pdf.gz)
EMICSS annotations (xml)

Tarantula venom peptide Protoxin-I bound to full-length human voltage-gated sodium channel 1.8 (NaV1.8)

EMD-46721

Single-particle
2.76 Å
EMD-46721
3D View Gallery
Deposition: 23/08/2024
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Thrixopelma pruriens
Sample: Sodium channel protein type 10 subunit alpha in complex with Beta/omega-theraphotoxin-Tp1a
Fitted models: 9dbn

Deposition Authors: Neumann B , McCarthy S, Gonen S
Structural basis of inhibition of human Na V 1.8 by the tarantula venom peptide Protoxin-I.
Neumann B , McCarthy S, Gonen S
(2025) Nat Commun , 16 , 1459 - 1459
PUBMED: 39920100
DOI: doi:10.1038/s41467-024-55764-z
ISSN: 2041-1723