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EMD-46715
MERS NTD-specific polyclonal antibodies
EMD-46715
Single-particle20.0 Å
Deposition: 23/08/2024Map released: 19/02/2025
Last modified: 19/02/2025
Sample Organism:
Middle East respiratory syndrome-related coronavirus
Sample: MERS spike protein complexed with RBD-depleted polyclonal Fabs from MERS-vaccinated mice sera
Deposition Authors: Ward AB, Bangaru S
Sample: MERS spike protein complexed with RBD-depleted polyclonal Fabs from MERS-vaccinated mice sera
Deposition Authors: Ward AB, Bangaru S
MERS-CoV spike vaccine-induced N-terminal domain-specific antibodies are more protective than receptor binding domain-specific antibodies.
Abiona OM,
Wang N,
Leist SR,
Schafer A,
Cockrell AS,
Wang L,
Bangaru S,
Stevens L,
Graham RL,
Kocher JF,
Tsybovsky Y,
Kanekiyo M,
Kumar A,
Morabito KM,
Rosen O,
Shi W,
Werner A,
Zhang Y,
Ziwawo C,
Dzuvor CKO,
Palandjian C,
Eastman C,
Matthews HR,
Joseph J 
,
Chappell JD,
Kong WP,
Mascola JR,
Ward AB,
Denison MR,
Baric R,
McLellan JS ,
Graham BS,
Corbett-Helaire KS
(2025) iScience , 28 , 111632 - 111632
,
Chappell JD,
Kong WP,
Mascola JR,
Ward AB,
Denison MR,
Baric R,
McLellan JS ,
Graham BS,
Corbett-Helaire KS
(2025) iScience , 28 , 111632 - 111632
Grant Support:
- Bill & Melinda Gates Foundation: OPP1170236 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): P01 AI110657 (United States)