EMD-46710

Single-particle
3.2 Å
EMD-46710
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Deposition: 23/08/2024
Map released: 09/07/2025
Last modified: 17/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46710
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Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S Do in proximal conformation (local refinement)

EMD-46710

Single-particle
3.2 Å
EMD-46710
3D View Gallery
Deposition: 23/08/2024
Map released: 09/07/2025
Last modified: 17/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Feline coronavirus
Sample: FCoV-23 S long: local refinement of D0 in proximal conformation.
Fitted models: 9db1

Deposition Authors: Tortorici MA , Veesler D , Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics.
Tortorici MA , Choi A, Gibson CA, Lee J, Brown JT, Stewart C , Joshi A, Harari S, Willoughby I, Treichel C, Leaf EM, Bloom JD , King NP , Tait-Burkard C , Whittaker GR, Veesler D
(2025) Nature , 645 , 235 - 243
PUBMED: 40634609
DOI: doi:10.1038/s41586-025-09155-z
ISSN: 1476-4687
ASTM: NATUAS