EMD-46686

Single-particle
3.4 Å
EMD-46686
3D View Gallery
Deposition: 21/08/2024
Map released: 11/06/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46686

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9d9z summary report (pdf.gz) Map-9d9z FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human UBR4-KCMF1-CaM E3 ligase complex (Silencing Factor of the Integrated stress response, SiFI)

EMD-46686

Single-particle
3.4 Å
EMD-46686
3D View Gallery
Deposition: 21/08/2024
Map released: 11/06/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Endogenous UBR4-KCMF1-CaM E3 Ligase complex (Silencing Factor of the Integrated stress response)
Fitted models: 9d9z

Deposition Authors: Yang Z , Rape M , Rape M
Molecular basis of SIFI activity in the integrated stress response.
Yang Z , Haakonsen DL, Heider M, Witus SR, Zelter A , Beschauner T, MacCoss MJ , Rape M
(2025) Nature , 643 , 1117 - 1126
PUBMED: 40328314
DOI: doi:10.1038/s41586-025-09074-z
ISSN: 1476-4687
ASTM: NATUAS