EMD-46649
Cryo-EM structure of the BG505 SOSIPv2
EMD-46649
Single-particle2.9 Å
Deposition: 20/08/2024Map released: 20/08/2025
Last modified: 12/11/2025
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: HIV-1 BG505 SOSIPv2 trimer
Fitted models: 9d8v
Deposition Authors: DeLaitsch AT
,
Bjorkman PJ
Sample: HIV-1 BG505 SOSIPv2 trimer
Fitted models: 9d8v
Deposition Authors: DeLaitsch AT
,
Bjorkman PJ
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy.
Gieselmann L,
DeLaitsch AT ,
Rohde M,
Gruell H,
Kreer C,
Ercanoglu MS,
Gristick HB,
Schommers P,
Ahmadov E,
Radford C,
Mazzolini A,
Zhang L,
West Jr AP,
Worczinski J,
Momot A,
Reichwein ML,
Knufer J,
Stumpf R,
Mkhize NN,
Kaldine H,
Bhebhe S,
Deshpande S,
Giovannoni F,
Stefanutti E,
Benigni F,
Havenar-Daughton C,
Corti D,
Kroidl A,
Adhikari A,
Nanfack AJ,
Ambada GE,
Duerr R,
Maganga L,
William W,
Ntinginya NE,
Wolf T,
Geldmacher C,
Hoelscher M,
Lehmann C,
Moore PL,
Mora T,
Walczak AM,
Gilbert PB,
Doria-Rose NA,
Huang Y,
Bloom JD,
Seaman MS,
Bjorkman PJ ,
Klein F
(2025) Nat Immunol , 26 , 2016 - 2029
,
Rohde M,
Gruell H,
Kreer C,
Ercanoglu MS,
Gristick HB,
Schommers P,
Ahmadov E,
Radford C,
Mazzolini A,
Zhang L,
West Jr AP,
Worczinski J,
Momot A,
Reichwein ML,
Knufer J,
Stumpf R,
Mkhize NN,
Kaldine H,
Bhebhe S,
Deshpande S,
Giovannoni F,
Stefanutti E,
Benigni F,
Havenar-Daughton C,
Corti D,
Kroidl A,
Adhikari A,
Nanfack AJ,
Ambada GE,
Duerr R,
Maganga L,
William W,
Ntinginya NE,
Wolf T,
Geldmacher C,
Hoelscher M,
Lehmann C,
Moore PL,
Mora T,
Walczak AM,
Gilbert PB,
Doria-Rose NA,
Huang Y,
Bloom JD,
Seaman MS,
Bjorkman PJ ,
Klein F
(2025) Nat Immunol , 26 , 2016 - 2029
Grant Support:
- Bill & Melinda Gates Foundation: INV-002143 (United States)