EMD-46601

Single-particle
3.02 Å
EMD-46601
3D View Gallery
Deposition: 16/08/2024
Map released: 04/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46601
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9d73 summary report (pdf.gz) Map and 9d73 FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of anti-MHC-I mAb B1.23.2 complex with HLA-B44:05

EMD-46601

Single-particle
3.02 Å
EMD-46601
3D View Gallery
Deposition: 16/08/2024
Map released: 04/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of Anti-human-mAb B1.23.2 and MHC-I HLA-B44:05
Fitted models: 9d73

Deposition Authors: Jiang J, Natarajan K, Lei H, Huang R, Margulies DH
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J, Panda AK, Natarajan K, Lei H, Sharma S, Boyd LF, Towler RR, Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N, Meier-Schellersheim M, Huang RK, Shevach EM, Margulies DH
(2026) Commun Biol
PUBMED: 41629525
DOI: doi:10.1038/s42003-026-09641-8
ISSN: 2399-3642