EMD-46596
Cryo-EM structure of E. coli FimH lectin domain bound to Fabs 440-2 and 454-3
EMD-46596
Single-particle4.24 Å
Deposition: 15/08/2024Map released: 05/02/2025
Last modified: 04/06/2025
Sample Organism:
Mus musculus,
Escherichia coli
Sample: FimH-DSG TM in complex with Fabs 440-2 and 445-3
Fitted models: 9d6f
Deposition Authors: Lees JA
,
Han S
Sample: FimH-DSG TM in complex with Fabs 440-2 and 445-3
Fitted models: 9d6f
Deposition Authors: Lees JA
,
Han S
Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
Silmon de Monerri NC ,
Che Y,
Lees JA ,
Jasti J,
Wu H,
Griffor MC,
Kodali S,
Hawkins JC,
Lypowy J,
Ponce C,
Curley K,
Esadze A,
Carcamo J,
McLellan T,
Keeney D,
Illenberger A,
Matsuka YV,
Shanker S,
Chorro L,
Gribenko AV,
Han S,
Anderson AS,
Donald RGK
(2025) PLoS Pathog , 21 , e1012325 - e1012325
,
Che Y,
Lees JA ,
Jasti J,
Wu H,
Griffor MC,
Kodali S,
Hawkins JC,
Lypowy J,
Ponce C,
Curley K,
Esadze A,
Carcamo J,
McLellan T,
Keeney D,
Illenberger A,
Matsuka YV,
Shanker S,
Chorro L,
Gribenko AV,
Han S,
Anderson AS,
Donald RGK
(2025) PLoS Pathog , 21 , e1012325 - e1012325
Grant Support:
- Other private: (United States)