EMD-46593

Single-particle
2.1 Å
EMD-46593
3D View Gallery
Deposition: 14/08/2024
Map released: 30/10/2024
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46593

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9d6c summary report (pdf.gz) Map-9d6c FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Gag CA-SP1 immature lattice bound with Lenacapavir and Bevirimat from enveloped virus like particles

EMD-46593

Single-particle
2.1 Å
EMD-46593
3D View Gallery
Deposition: 14/08/2024
Map released: 30/10/2024
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE), Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)
Sample: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Fitted models: 9d6c

Deposition Authors: Wu C , Meuser ME , Xiong Y
Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat.
Wu C , Meuser ME , Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
(2025) J Am Chem Soc , 147 , 42685 - 42700
PUBMED: 41198571
DOI: doi:10.1021/jacs.5c13735
ISSN: 1520-5126
ASTM: JACSAT