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EMD-46483
A widespread heme dechelatase in healthy and pathogenic human microbiomes.
EMD-46483
Single-particle2.6 Å
Deposition: 08/08/2024Map released: 20/08/2025
Last modified: 24/12/2025
Sample Organism:
Bacteroides thetaiotaomicron,
Bacteroides
Sample: HmuS in complex with heme
Fitted models: 9d26
Deposition Authors: Gauvin CC
,
Nath AK,
Rodrigues da Silva R,
Akpoto E
,
Dubois JL,
Lawrence CM
Sample: HmuS in complex with heme
Fitted models: 9d26
Deposition Authors: Gauvin CC
,
Nath AK,
Rodrigues da Silva R,
Akpoto E
,
Dubois JL,
Lawrence CM
Commensal gut bacteria employ de-chelatase HmuS to harvest iron from heme.
Kumar Nath A
,
da Silva RR
,
Gauvin CC
,
Akpoto E
,
Dlakic M
,
Lawrence CM
,
DuBois JL
(2025) EMBO J , 44 , 6226 - 6252
,
da Silva RR
,
Gauvin CC
,
Akpoto E
,
Dlakic M
,
Lawrence CM
,
DuBois JL
(2025) EMBO J , 44 , 6226 - 6252
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): (United States)
- National Science Foundation (NSF, United States): DBI-1828765 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P30GM140963 (United States)
