Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-46483

Single-particle
2.6 Å
EMD-46483 Deposition: 08/08/2024
Map released: 20/08/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46483

A widespread heme dechelatase in healthy and pathogenic human microbiomes.

EMD-46483

Single-particle
2.6 Å
EMD-46483 Deposition: 08/08/2024
Map released: 20/08/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bacteroides thetaiotaomicron, Bacteroides
Sample: HmuS in complex with heme
Fitted models: 9d26

Deposition Authors: Gauvin CC , Nath AK, Rodrigues da Silva R, Akpoto E , Dubois JL, Lawrence CM
Commensal gut bacteria employ de-chelatase HmuS to harvest iron from heme.
Kumar Nath A , da Silva RR , Gauvin CC , Akpoto E , Dlakic M , Lawrence CM , DuBois JL
(2025) EMBO J , 44 , 6226 - 6252
PUBMED: 40940422
DOI: doi:10.1038/s44318-025-00563-5
ISSN: 1460-2075
ASTM: EMJODG