EMD-46448

Single-particle
3.1 Å
EMD-46448
3D View Gallery
Deposition: 06/08/2024
Map released: 07/05/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46448

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9d0a summary report (pdf.gz) Map-9d0a FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of PAR2 with endogenous tethered ligand.

EMD-46448

Single-particle
3.1 Å
EMD-46448
3D View Gallery
Deposition: 06/08/2024
Map released: 07/05/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, unidentified
Sample: Complex of PAR2 with G proteins
Fitted models: 9d0a

Deposition Authors: Lyu Z, Lyu X, McGrath AP , Kang Y
Structural basis for the activation of proteinase-activated receptors PAR1 and PAR2.
Lyu Z, Lyu X, Malyutin AG , Xia G, Carney D , Alves VM , Falk M, Arora N, Zou H, McGrath AP , Kang Y
(2025) Nat Commun , 16 , 3931 - 3931
PUBMED: 40287415
DOI: doi:10.1038/s41467-025-59138-x
ISSN: 2041-1723
Grant Support: