Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-46422

Helical reconstruction
2.6 Å
EMD-46422
3D View Gallery
Deposition: 05/08/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46422
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9czn summary report (pdf.gz) Map and 9czn FULL report (pdf.gz)
EMICSS annotations (xml)

Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques

EMD-46422

Helical reconstruction
2.6 Å
EMD-46422
3D View Gallery
Deposition: 05/08/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Type Ic amyloid-beta 42
Fitted models: 9czn

Deposition Authors: Hoq MR, Vago FS, Ozcan KA, Bharath SR
Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Hoq MR, Fernandez A, Vago FS, Hallinan GI, Bharath SR, Li D, Ozcan KA, Garringer HJ, Jiang W , Vidal R , Ghetti B
(2024) Acta Neuropathol , 148 , 20 - 20
PUBMED: 39147931
DOI: doi:10.1007/s00401-024-02786-y
ISSN: 1432-0533