Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-46420

Helical reconstruction
2.9 Å
EMD-46420 Deposition: 05/08/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46420

Straight tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques

EMD-46420

Helical reconstruction
2.9 Å
EMD-46420 Deposition: 05/08/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Straight tau filament
Fitted models: 9czl

Deposition Authors: Hoq MR, Vago FS, Ozcan KA, Bharath SR
Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Hoq MR, Fernandez A, Vago FS, Hallinan GI, Bharath SR, Li D, Ozcan KA, Garringer HJ, Jiang W , Vidal R , Ghetti B
(2024) Acta Neuropathol , 148 , 20 - 20
PUBMED: 39147931
DOI: doi:10.1007/s00401-024-02786-y
ISSN: 1432-0533